T7204-25MG Display Image

Toremifene citrate salt, >=98% (HPLC)

Code: T7204-25MG D2-231

Application

Toremifene citrate salt has been used:in cell-based ELISAas a positive control to detect its antiviral activity against Ebola virus (EBOV)to treat MCF7 and T47D b...


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£260.00 25MG
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Application

Toremifene citrate salt has been used:in cell-based ELISAas a positive control to detect its antiviral activity against Ebola virus (EBOV)to treat MCF7 and T47D breast cancer cell lines

Biochem/physiol Actions

Toremifene citrate is an oral selective estrogen receptor modulator (SERM). It is used in advanced (metastatic) breast cancer and being evaluated for prevention of prostate cancer. Toremifene citrate is known to increase bone mineral density in prostate cancer patients undergoing androgen deprivation therapy†.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

General description

Toremifene is a triphenylethylene derivative. It exhibits antitumor and antiestrogen effects. Toremifene has estrogen-agonist effects on blood lipids and endometrium.

Packaging

5, 25 mg in glass bottle

Preparation Note

Toremifene citrate salt is soluble in DMSO at a concentration that is greater than 10 mg/ml.

assay≥98% (HPLC)
colorwhite to off-white
formpowder
Gene Informationhuman ... ESR1(2099), ESR2(2100)
InChI keyIWEQQRMGNVVKQW-OQKDUQJOSA-N
InChI1S/C26H28ClNO.C6H8O7/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-16H,17-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-;
Quality Level100
SMILES stringOC(=O)CC(O)(CC(O)=O)C(O)=O.CN(C)CCOc1ccc(cc1)C(=C(CCCl)c2ccccc2)c3ccccc3
solubilityDMSO: >10 mg/mL
storage conditiondesiccated
storage temp.2-8°C
Code
Description
Unit Size
List Price
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T7204-5MG
Toremifene citrate salt, >=98% (HPLC)

Unit:5MG
List Price: £72.20
Source:List Price
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Cas Number89778-27-8
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