Biochem/physiol Actions

Opsin3 controls the apoptotic pathway and makes hepatocellular carcinoma cells fragile to 5-fluorouracil treatment. OPN3 plays an important role in oncogenesis and drug resistance. It also plays crucial roles in various physiological and pathological processes.

Features and Benefits

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General description

Anti-OPN3 Antibody detects endogenous levels of total OPN3 protein.

Opsin 3 (OPN3) is also termed as encephalopsin or panopsin. It is a member of the encephalopsin/tmt-opsin subfamily. It is expressed in brain, liver, placenta, heart and pancreatic tissues. The OPN3 gene is located on human chromosome 1q43.

Immunogen

The antiserum was produced against synthesized peptide derived from human OPN3.Immunogen Range: 161-210

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.