Biochem/physiol Actions

Polymorphism in mitochondrially encoded cytochrome c oxidase II (MT-CO2) might alter electron transfer from cytochrome c to the bimetallic center of the catalytic subunit I. Aberrations in MT-CO2 expression has been observed in prostate cancer patients.

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General description

Mitochondrially encoded cytochrome c oxidase II (MT-CO2) is a key subunit of cytochrome c oxidase, which is the terminal enzyme involved in the oxidative phosphorylation complexes.

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human mitochondrially encoded cytochrome c oxidase II

Physical form

Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

Specificity

The antibody detects endogenous levels of total MT-CO2 protein.