Application
Anti-BST-2 (CD317), clone 927, Cat. No. MABF2047, is a rat monoclonal antibody that detects Bone marrow stromal antigen 2 and has been tested for use in ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), and Neutralizing activity.
Neutralizing Analysis: A representative lot efficiently depleted type I interferon-producing cells (IPC) and abrogated IFN-alpha secretion by IPC in response to CpG. (Blasius, A.L., et. al. (2006). J Immunol. 177(5):3260-5).
Immunohistochemistry (Paraffin) Analysis: A representative lot detected BST-2 (CD317) in Immunohistochemistry applications (Yun, T., et. al. (2016). Cell Metab. 23(5):852-66).
ELISA Analysis: A representative lot detected BST-2 (CD317) in ELISA applications (Blasius, A.L., et. al. (2006). J Immunol. 177(5):3260-5).
Flow Cytometry Analysis: A representative lot detected BST-2 (CD317) in Flow Cytometry applications (Blasius, A.L., et. al. (2006). J Immunol. 177(5):3260-5; Yun, T., et. al. (2016). Cell Metab. 23(5):852-66).
Immunogen
Type I IFN-producing cells derived from mouse bone marrow.
Other Notes
Concentration: Please refer to lot specific datasheet.
Physical form
Format: Purified
Quality
Evaluated by Immunohistochemistry (Paraffin) in mouse spleen and mouse kidney tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:25 dilution of this antibody detected BST-2 (CD317) in mouse spleen and mouse kidney tissue sections.
Specificity
Clone 927 is a rat monoclonal antibody that specifically detects murine Bone marrow stromal antigen 2 (BST-2). It targets an epitope with in the extracellular domain.
Target description
~19.15 kDa calculated.
This product has met the following criteria: