Application

Anti-APOB antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. It may also be used for serum lipid analyses and apolipoprotein assays.

Biochem/physiol Actions

Apolipoprotein B (apoB) is the main protein component of triacylglyceride (TAG)-rich lipoproteins. It includes chylomicrons as well as very low density lipoprotein (the "bad cholesterol"). The N-terminal domains of apoB support the intrinsic capability of co-translational lipid recruitment. Apolipoprotein B is considered as a key structural component of all the atherogenic lipoproteins and its genetic variation may affect plasma ApoB and lipid levels, which may influence atherogenesis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Apolipoprotein B-100 native protein.

Immunogen Sequence: GI # 4502153, sequence 1-4563

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.