D2915-100MG Display Image
D2915-100MG Display Image

Dexamethasone-Water Soluble, suitable for cell culture, BioReagent

Code: D2915-100MG D2-231

Application

Dexamethasone-Water Soluble has been used as a component of• Dulbecco's modified Eagle medium based osteogenic and adipogenic medium for human mesenchymal stem ce...

read more

£178.00 100MG
List Price

Application

Dexamethasone-Water Soluble has been used as a component of• Dulbecco's modified Eagle medium based osteogenic and adipogenic medium for human mesenchymal stem cell culture• erythroid expansion media for the growth of liver, bone marrow and spleen tissues• medium 199 (M199) for hepatocyte culture

Biochem/physiol Actions

Dexamethasone is an anti-inflammatory glucocorticoid and a synthetic corticosteroid used for treating corneal inflammation. It inhibits the IL-1ß-dependent angiogenesis. Dexamethasone elicits a range of effects on cell survival, cell signaling and gene expression. It favors apoptosis in chondrocytes and impairs development of bone. Dexamethasone is a potential therapeutic agent as it induces apoptosis in multiple myeloma (MM) cells. It elicits its functionality by lowering glucocorticoid receptor (GR) a levels and inhibits colon tumor progression.

Other Notes

Contains approx. 65 mg dexamethasone per gram; balance methyl-β-cyclodextrin.

Packaging

Package size based on dexamethasone

100 mg in glass bottle

Quality Level200
InChI keyXEJNDGTUKUMQNG-ARJMFYCQSA-N
product lineBioReagent
InChI1S/C42H70O35.C22H30O4/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51;1-12-8-16-15-5-4-13-9-14(24)6-7-21(13,2)20(15)17(25)10-22(16,3)19(12)18(26)11-23/h8-63H,1-7H2;6-7,9,12,15-17,19-20,23,25H,4-5,8,10-11H2,1-3H3/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-;12-,15+,16?,17+,19-,20-,21+,22+/m11/s1
formsolid
storage temp.room temp
solubilityH2O: 25 mg/mL, clear to slightly hazy
application(s)cell culture | mammalian: suitable
SMILES stringC[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO.OC[C@H]5O[C@@H]6O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]9[C@H](O)[C@@H](O)[C@H](O[C@@H]9CO)O[C@H][C@H](O)[C@@H](O)[C@H](O[C@@H]CO)O[C@H][C@H](O)[C@@H](O)[C@H](O[C@@H]CO)O[C@H][C@H](O)[C@@H](O)[C@H](O[C@@H]CO)O[C@H]5[C@H](O)[C@H]6O

Cas Number50-02-2