Application

Dobutamine hydrochloride has been used: to treat mouse embryonic fibroblasts for cell death analysis to inhibit TAZ (transcriptional coactivator with PDZ-binding motif)/YAP (Yes-associated protein) of Hippo pathway and study its effect on tumor cell proliferation as β1-AR partial agonist to determine its effects on budding of endophilin-mRFP-positive structures by live-cell imaging

Biochem/physiol Actions

Dobutamine is a synthetic catecholamine that stimulate the β1 -adrenoceptor receptor. It exhibits inotropic outcome on the myocardium. Dobutamine elevates contractility and is known to be useful in the condition of low blood pressure.

Features and Benefits

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.