Analysis Note

The biological activity is measured by its ability to induce alkaline phosphatase production using mouse ATDC-5 chondrogenic cells.

Biochem/physiol Actions

Cellular responses to BMP-7 are mediated by the formation of hetero-oligomeric complexes of type I and II serine/threonine kinase receptors. Human and mouse BMP-7 share 98% amino acid sequence identity.

Physical form

Lyophilized from 50.0 µl of a 0.2 µm filtered solution in 35% acetonitrile, 0.1% TFA containing 50 µg bovine serum albumin per 1µg of cytokine.