A9518-25G Display Image

Ampicillin sodium salt,

Code: A9518-25G 507

Ampicillin is reported as slightly soluble in water, practically insoluble in alcohol, chloroform, ether and fixed oils but soluble in dilute acids or bases. The solution should not be autoclaved; ...

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Ampicillin is reported as slightly soluble in water, practically insoluble in alcohol, chloroform, ether and fixed oils but soluble in dilute acids or bases. The solution should not be autoclaved; a stock solution should be sterilized through filtration and stored frozen, where it will be stable for months.

Caution: This product has been reported stable as supplied at 25°C at 43% and 81% relative humidity for six weeks. Additional studies have shown that the stability of Ampicillin in solution is a function of pH, temperature and the identity of the buffer. It′s activity is quickly lost when stored above pH 7. Optimal storage conditions are suggested as 2-8°C, and pH 3.8-5 where its activity was retained at 90%+ for a week.

  • Synonym: D-(−)-α-Aminobenzylpenicillin sodium salt
  • CAS Number: 69-52-3
  • Empirical Formula (Hill Notation): C16H18N3NaO4S
  • Molecular Weight: 371.39
  • Beilstein Registry Number: 4119211
  • EC Number: 200-708-1
  • MDL Number: MFCD00064313
  • PubChem Substance ID: 24891463
  • InChI Key: KLOHDWPABZXLGI-YWUHCJSESA-M
  • Form: Powder
  • Colour: White to slight yellow
  • mp: 215 °C (dec.) (lit.)
  • Solubility: H2O: 50 mg/mL
  • Featured Industry: Agriculture
  • Mode of Action: Cell wall synthesis | interferes
  • Antibiotic Activity Spectrum: Gram-negative bacteria, Gram-positive bacteria
  • Storage Temp.: 2-8°C
  • Chemical Structure: ß-lactam
  • Storage:
  • Mode of Action: This is a ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane
  • Mode of Resistance: Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it
  • Antimicrobial Spectrum: Includes both gram-positive (similar to benzylpenicillin) and gram-negative bacteria (similar to tetracyclines and chloramphenicol)
Synonym
D-(−)-α-Aminobenzylpenicillin sodium salt
CAS Number
69-52-3
Empirical Formula (Hill Notation)
C16H18N3NaO4S
Molecular Weight
371.39
Beilstein Registry Number
4119211
EC Number
200-708-1
MDL Number
MFCD00064313
PubChem Substance ID
24891463
InChI Key
KLOHDWPABZXLGI-YWUHCJSESA-M
Form
Powder
Color
White to slight yellow
mp
215 °C (dec.) (lit.)
Solubility
H2O: 50 mg/mL
Featured Industry
Agriculture
Mode of Action
Cell wall synthesis | interferes
Antibiotic Activity Spectrum
Gram-negative bacteria
Gram-positive bacteria
Storage Temp.
2-8°C
Chemical Structure
ß-lactam
Storage
Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids
Mode of Action
ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane
Mode of Resistance
Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it
Antimicrobial Spectrum
Both gram-positive (similar to benzylpenicillin) and gram-negative bacteria (similar to tetracyclines and chloramphenicol)
Code
Description
Unit Size
List Price
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A9518-100G
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£461.00
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A9518-5G
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£40.90
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