85588-5G Display Image

Spermine dihydrate, BioUltra, >=99.5% (GC)

Code: 85588-5G D2-231

Biochem/physiol Actions

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is ...


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Biochem/physiol Actions

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Other Notes

Polyamines: Review; Inhibitor of ATPase; DNA polymerase; ribonuclease

λ1 M in H2O
anion tracessulfate (SO42-): ≤50 mg/kg, chloride (Cl-): ≤50 mg/kg
assay≥99.5% (GC)
cation tracesBi: ≤5 mg/kg, Na: ≤50 mg/kg, Mo: ≤5 mg/kg, Al: ≤5 mg/kg, K: ≤50 mg/kg, As: ≤0.1 mg/kg, Li: ≤5 mg/kg, Cr: ≤5 mg/kg, Mn: ≤5 mg/kg, Sr: ≤5 mg/kg, Mg: ≤5 mg/kg, Ca: ≤10 mg/kg, Pb: ≤5 mg/kg, Cu: ≤5 mg/kg, Ba: ≤5 mg/kg, Fe: ≤5 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg
formpowder
impuritiesinsoluble matter, passes filter test
InChI keyMTNRSMVAYLLBAV-UHFFFAOYSA-N
InChI1S/C10H26N4.2H2O/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;/h13-14H,1-12H2;2*1H2
mp63-64 °C
pH12.0-13.5 (25 °C, 1 M in H2O)
product lineBioUltra
Quality Level100
SMILES stringO.O.NCCCNCCCCNCCCN
solubilityH2O: 1 M at 20 °C, clear, colorless
storage temp.2-8°C
UV absorptionλ: 280 nm Amax: 0.20, λ: 260 nm Amax: 0.20
Cas Number403982-64-9
Hazard Class8
Un Number3259
Pack GroupII
This product has met the following criteria: