Application
Spermidine trihydrochloride has been used as standard for the detection of biogenic amines using HPLC.
Biochem/physiol Actions
Spermidine modulates various cellular activities like cellular development and differentiation, stability of DNA and apoptosis.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
General description
Spermidineis a polyamine and a trivalent organic cation.
This product has met the following criteria: