Analysis Note

Colour (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (determined from the substitution of the Fmoc-Ala-Leu loaded resin): 1.00 - 1.80 mmol/gSwelling Volume (in CH₂Cl₂): 2.0 - 5.0 ml/gTotal swelling volume acc. Houben Weyl (in CH₂Cl₂): ≥ 4.2 ml/gThe polymer matrix is copoly (styrene-1 % DVB) 100 - 200 mesh.

General description

An extremely versatile, acid-labile resin for the solid phase immobilization of carboxylic acids [1-6, 20], alcohols [7-9, 20], phenols [10-13, 20] and amines [14-20], imidazoles [20] and hydroxylamines [21, 22].

Release of these functionalities is generally achieved using 1-50% TFA in DCM containing 5% TIS, although carboxylic acids can also be cleaved from this support with AcOH/TFE/DCM [1-6], 0.5% TFA in DCM, or HFIP in DCM [23].

The product number for this product was previously 01-64-0114.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 01-64-0114