Analysis Note
Color (visual): light yellow to yellow to beigeAppearance of substance (visual): beadsLoading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.10 - 0.25 mmol/gSwelling Volume (in DMF): lot specific resultThe polymer matrix is NovaSyn TG resin (130µm)
General description
NovaSyn™ TG Sieber resin consists of 130 μm NovaSyn™ TG bromo resin derivatized with Sieber′s xanhydrylamine linker [1, 2]. This resin is ideal for the Fmoc SPPS of partially protected peptide amide fragments. Cleavage from this support is effected by treatment with 1% TFA in DCM, conditions that leave most standard side-chain protecting groups intact.
This resin can be reductively alkylated and used to prepare secondary carboxamides [3]. It can also be employed to produce protected peptide fragments in which the C-terminal carboxylic acid group is blocked as a hydroxymethylphenoxy-β-alaninamide ester [4].
The product number for this product was previously 01-64-0092.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Legal Information
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Linkage
Replaces: 01-64-0092
This product has met the following criteria: