Analysis Note

Color (visual): white to pale yellow to beigeAppearance of substance (visual): beadsLoading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/gTNBS-Test: passes testSwelling Volume (in DMF): lot specific resultSwelling Volume (in CH₂Cl₂): lot specific resultTotal swelling volume acc. Houben Weyl (in CH₂Cl₂): ≥ 5.2 ml/gTotal swelling volume acc. Houben Weyl (in DMF): ≥ 5.2 ml/gThe polymer matrix is copoly (styrene-1 % DVB) 100 - 200 mesh.

General description

An excellent support for the Fmoc SPPS of peptide amides.

This resin is more acid sensitive than Rink Amide AM and Rink Amide MBHA resins. Cleavage with high concentrations of TFA can lead to the breakdown of the linker, with the concomitant formation of by-products that can not be removed by simple washes. These problems appear to be minimized through the use of low TFA concentrations or by the addition of trialkylsilanes to the cleavage mixture.

The product number for this product was previously 01-64-0013.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 01-64-0013

Packaging

5 g in Glass bottle

25 g in Plastic bottle