Analysis Note

purity : ≥96.0% (HPLC)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Tenuazonic acid may be used as an analytical reference standard for the quantification of the analyte in the following:Cornflakes using high-performance liquid chromatography (HPLC) technique.Human urine samples using isotope dilution assay method and liquid chromatography coupled to a hybrid triple quadrupole/linear ion trap mass spectrometer.Cereals using high-performance liquid chromatography–electrospray ionization ion-trap multistage mass spectrometry (HPLC- ESI ion-trap (IT) MS²). ESI Fourier transform-ion cyclotron resonance tandem mass spectrometry (FTICR-MS²) technique is used for product characterization, post derivatization with 2,4-dinitrophenylhydrazine.

General description

Tenuazonic acid is a biologically active compound and its mode of action involves the inhibition of protein biosynthesis.

Tenuazonic acid is a mycotoxin, which belongs to the class of tetramic acids, the largest family of natural products. It is generally isolated from phytopathogenic fungal species like Alternaria alternata, A. longipes and A. tenuissima.

Reconstitution

Dried down, ~100 µg/mL after reconstitution with 1 mL of water