Application

5-Fluoroisatin may be used:as reaction-based probe for live-cell detection of peroxynitrite by ¹⁹F magnetic resonance spectroscopyin non-invasive detection of peroxynitrite (ONOO(-)) formation in living lung epithelial cells stimulated with interferon-γ (IFN-γ)in the synthesis of bis-Schiff bases, via condensation with aromatic primary bis-amines in water suspension medium without using any organic solvent or acid catalystin the synthesis of 3-acetonyl-5-fluoro-3-hydroxyoxindole

Reactant for preparation of:•Spiro[indole-thiazolidinones] as biologically relevan synthesis scaffolds•Potential antimycobacterial agents•Inhibitors of c-Met kinase•Inhibitors of TAK1 kinase•Herpes simplex virus inhibitors•IKKβ inhibitors•Inhibitors of vitiligo disease•Potential drug candidates with anti-HIV activity and anti-tubercular activity

General description

5-Fluoroisatin has been reported as the precursor of the Sunitinib (Sutent) drug. 5-Fluoroisatin has been approved by the Food and Drugs Administration (FDA) in 2006 for the treatment of renal cell carcinoma (RCC) and gastrointestinal stromal tumor (GIST).

Packaging

5 g in glass bottle