General description

Immunolabelling of neurofilaments (NF) is employed for study of nerve distribution of normal and abnormal tissues, and neuronal differentiation of neoplasms. NF are found in neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, neuroblastomas, and retinoblastomas. Neurofilaments are also present in paragangliomas, as well as, adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and lung small cell carcinoma also express neurofilament.^1-5

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

Neurofilament Positive Control Slides, Product No. 302S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide.

Preparation Note

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Quality