D1262-50MG Display Image
D1262-50MG Display Image

P1,P4-Di(adenosine-5) tetraphosphate ammonium salt, >=95% (HPLC), powder

Code: D1262-50MG D2-231

Application

P1,P4-Di(adenosine-5') tetraphosphate ammonium salt has been used as a substrate for nudix hydrolyse. It has also been used as a ATP analog and nudix substrate fo...

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£208.98 50MG
List Price

Application

P1,P4-Di(adenosine-5') tetraphosphate ammonium salt has been used as a substrate for nudix hydrolyse. It has also been used as a ATP analog and nudix substrate for cleavage factor II Im25 subunit.

Biochem/physiol Actions

Diadenosine polyphosphate (Ap4A) functions as a second messenger in pancreatic cells. Diadenosine polyphosphate is majorly stored in neuronal cells, thrombocytes and chromaffin. It stimulates phospholipase D, fluctuates intracellular calcium levels, induces nitric oxide release, activates 5'-nucleotidase, and inhibits adenosine kinase activity in vitro. The membrane-bound ectoenzymes in endothelial cells in blood plasma and smooth muscle cell metabolize Ap4A.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Packaging

10, 50 mg in glass bottle

InChI keyJTLRVYSRZSPJKJ-AHKIGRPSSA-N
Quality Level200
assay95% (HPLC)
SMILES stringN.Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)n5cnc6c(N)ncnc56)[C@@H](O)[C@H]3O
InChI1S/C20H28N10O19P4.H3N/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(45-19)1-43-50(35,36)47-52(39,40)49-53(41,42)48-51(37,38)44-2-8-12(32)14(34)20(46-8)30-6-28-10-16(22)24-4-26-18(10)30;/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H2,21,23,25)(H2,22,24,26);1H3/t7-,8-,11-,12-,13-,14-,19-,20-;/m1./s1
Gene Informationhuman ... PLD1(5337), PLD2(5338), PLD3(23646), PLD4(122618), PLD5(200150)
formpowder
solubilityH2O: 50 mg/mL
storage temp.20C
colorwhite to off-white

Code
Description
Unit Size
List Price
Qty
D1262-10MG
Unit:10MG
List Price: £57.65
Source:List Price
ADD
Cas Number102783-36-8