01885-25MG-F Display Image

Docetaxel, purum, >=97.0% (HPLC)

Code: 01885-25MG-F D2-231

Application

Docetaxel can be used to study antibiotics, cell biology, cell signaling, neuroscience and apoptosis and the cell cycle. Docetaxel has been used to study the prev...

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£337.00 25MG
List Price

Application

Docetaxel can be used to study antibiotics, cell biology, cell signaling, neuroscience and apoptosis and the cell cycle. Docetaxel has been used to study the prevention of chemotherapy-induced alopecia, as well as the treatment of non-small-cell lung cancer in patients contraindicated for standard chemotherapy. Docetaxel has also been used to study the role of hypoxia-inducible factor-1α and -2α in androgen insensitive prostate cancer cells.

Biochem/physiol Actions

Docetaxel is a taxane anti-cancer agent related to paclitaxel. It binds to and stabilizes the β−tubulin subunit of microtubules, preventing depolymerization of the mitotic spindle thus leading to cell cycle arrest and apoptosis.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

InChI keyZDZOTLJHXYCWBA-VCVYQWHSSA-N
Quality Level200
formpowder or crystals
SMILES string[H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](O)C4=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c6ccccc6
mp186-192 °C (dec.)
InChI1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32+,33-,35-,41+,42-,43+/m0/s1
assay≥97.0% (HPLC)
impurities~6% water
gradepurum

Code
Description
Unit Size
List Price
Qty
01885-5MG-F
Unit:5MG
List Price: £96.30
Source:List Price
ADD
Cas Number114977-28-5