D0676-10MG Display Image
D0676-10MG Display Image

Dobutamine hydrochloride, >=98%

Code: D0676-10MG D2-231

Application

Dobutamine hydrochloride has been used: • to treat mouse embryonic fibroblasts for cell death analysis• to inhibit TAZ (transcriptional coactivator with PDZ-bind...

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£78.87 10MG
List Price

Application

Dobutamine hydrochloride has been used: • to treat mouse embryonic fibroblasts for cell death analysis• to inhibit TAZ (transcriptional coactivator with PDZ-binding motif)/YAP (Yes-associated protein) of Hippo pathway and study its effect on tumor cell proliferation• as ß1-AR partial agonist to determine its effects on budding of endophilin-mRFP-positive structures by live-cell imaging

Biochem/physiol Actions

Dobutamine is a synthetic catecholamine that stimulate the ß1 -adrenoceptor receptor. It exhibits inotropic outcome on the myocardium. Dobutamine elevates contractility and is known to be useful in the condition of low blood pressure.

Features and Benefits

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Quality Level200
storage temp.2-8C
originatorEli Lilly
assay98%
Gene Informationhuman ... ADRB1(153), ADRB2(154)
InChI keyBQKADKWNRWCIJL-UHFFFAOYSA-N
InChI1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H
SMILES stringCl[H].CC(CCc1ccc(O)cc1)NCCc2ccc(O)c(O)c2

Code
Description
Unit Size
List Price
Qty
D0676-50MG
Unit:50MG
List Price: £262.54
Source:List Price
ADD
Cas Number49745-95-1