D2390-100MG Display Image
D2390-100MG Display Image

Dacarbazine, antineoplastic purine analog

Code: D2390-100MG D2-231

Application

Dacarbazine is a triazine antineoplastic agent that is used for DNA methylation via formation of methyl adducts. It is used to treat metastatic malignant melanoma...

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£58.60 100MG
List Price

Application

Dacarbazine is a triazine antineoplastic agent that is used for DNA methylation via formation of methyl adducts. It is used to treat metastatic malignant melanomas and Hodgkin′s when used in combination with other antineoplastic agents.

Biochem/physiol Actions

Dacarbazine is a purine analog of naturally occurring purine precursor 5-amino-1H-imidazole-4-carboxamide (AIC). It is a synthetic triazine antineoplastic agent that exerts cytotoxic effects by acting as an alkylating agent and by inhibiting DNA synthesis and inducing apoptosis. It is known to induce hepatotoxicity in mice. Dacarbazine is not cell cycle-phase specific.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Packaging

1 g in glass bottle

100 mg in glass bottle

InChI1S/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)/b11-10+
antibiotic activity spectrumneoplastics
solubility1 M HCl: 50 mg/mL
storage temp.2-8C
InChI keyFDKXTQMXEQVLRF-ZHACJKMWSA-N
Mode of actionDNA synthesis | interferes
formpowder
SMILES stringCN(C)N=Nc1[nH]cnc1C(N)=O
Quality Level100

Code
Description
Unit Size
List Price
Qty
D2390-1G
Unit:1G
List Price: £318.00
Source:List Price
ADD
Cas Number4342-03-4